Tadalafil inhibits the enzyme PDE5, which normally breaks down cyclic guanosine monophosphate (cGMP) in the penis. This inhibition allows cGMP to accumulate and promote relaxation of blood vessels in the penis, thereby facilitating an erection when sexually aroused.Tazzle 20 FM refers to the amount of Tadalafil in each tablet, specifically 20 mg. This dosage is generally recommended for men who require treatment for ED.